E-Abstract

Lots of interesting abstracts and cases were submitted for TCTAP 2026. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge!

ABS20251112_0005

Starting a New Procedure Is Never Easy: Procedural and Clinical Outcomes After Leaflet Modification and TAVR

By Huan-Chiu Lin, Yung-Tsai Lee, Tien-Ping Tsao, Wei Hsian Yin

Presenter

Huan-Chiu Lin

Authors

Huan-Chiu Lin1, Yung-Tsai Lee1, Tien-Ping Tsao1, Wei Hsian Yin1

Affiliation

Cheng Hsin General Hospital, Taiwan1
View Study Report
ABS20251112_0005
Complex TAVR

Starting a New Procedure Is Never Easy: Procedural and Clinical Outcomes After Leaflet Modification and TAVR

Huan-Chiu Lin1, Yung-Tsai Lee1, Tien-Ping Tsao1, Wei Hsian Yin1

Cheng Hsin General Hospital, Taiwan1

Background

Leafletmodification techniques such as BASILICA and UNICORN use percutaneouselectrocautery to lacerate diseased aortic valve leaflets prior totranscatheter aortic valve replacement (TAVR), aiming to prevent coronaryobstruction. We report the feasibility and safety of TAVR following leafletmodification at our institution.

Methods

Between2023 and 2025, 14 high-risk patients underwent TAVR with BASILICA or UNICORN.Of these, 6/14 (43%) had failed surgical or transcatheter bioprosthetic valves,and 8/14 (57%) had native valve stenosis. Balloon-expandable valves were usedin 60% and self-expanding valves in 40% of cases; cerebral protection wasapplied in all patients.

Results

Technical success (successful leafletlaceration) was achieved in 11/14 (79%). Procedural success (effectiveBASILICA/UNICORN with survival free from coronary obstruction, emergencysurgery, or reintervention) was observed in 9/14 (64%). One patient (7%)developed coronary obstruction despite BASILICA and required surgicalconversion. There were no procedural deaths. At 30 days, mortality was 2/14(14%), with no strokes reported. Outcomes did not differ between patients withbioprosthetic versus native valves, though subgroup analyses were limited bysmall sample size and potential selection bias.

Conclusion

Thissingle-center real-world experience suggests that leaflet modification is asafe and potentially effective strategy to reduce coronary obstruction risk inselected patients undergoing TAVR, despite limitations related to sample sizeand study design.