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Lots of interesting abstracts and cases were submitted for TCTAP 2024. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP C-049

Challenging Case of CTO for Patient With Anaphylactic Shock Against Iodinated-Based Contrast

By Tsuda Takuma, Nao Yasuda, Satoru Sumitsuji

Presenter

Tsuda Takuma

Authors

Tsuda Takuma1, Nao Yasuda1, Satoru Sumitsuji2

Affiliation

Nagoya Ekisaikai Hospital, Japan1, Osaka University, Japan2,
View Study Report
TCTAP C-049
Coronary - Complex PCI - CTO

Challenging Case of CTO for Patient With Anaphylactic Shock Against Iodinated-Based Contrast

Tsuda Takuma1, Nao Yasuda1, Satoru Sumitsuji2

Nagoya Ekisaikai Hospital, Japan1, Osaka University, Japan2,

Clinical Information

Patient initials or Identifier Number

Relevant Clinical History and Physical Exam

A 41-year-old-male presented to our hospital due to chest pain during exertion. He had history of dyslipidemia, obesity, paroxysmal atrial fibrillation and several PCIs; Proximal right coronary artery (RCA) and mid left anterior descending artery (LAD) and distal left circumflex artery (LCx) already was implanted DESs. He had history of anaphylactic shock for iodine-based contrast during last CAG, which could reveal long CTO including in-stent in LAD and not significant stenosis in RCA and LCx.

Relevant Test Results Prior to Catheterization

LAD showed viable with resting single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) by using electrocardiography-gated technetium-99m (Tc-99m). This patient¡¯s symptoms were considered to related to LAD coronary occlusion, and months-long medical therapy appeared to be insufficient. We discussed with heart team, and finally scheduled PCI by using Ga-based contrast

Relevant Catheterization Findings

He had history of anaphylactic shock for iodine-based contrast during last CAG, which could reveal long CTO including in-stent in LAD and not significant stenosis in RCA and LCx. D1 branch supply collateral flow into both residual island inside mid-CTO via D3 branch, and LAD distal via tiny apical channel, respectively. However, distal true lumen was ambiguous via collateral channel flow by diagnostic catheter injection.

Interventional Management

Procedural Step

1:  Compared the pure and half diluted Gd-based contrast with iodine-based contrast2:  Punctured CTO entry with Confienza Pro12 with Corsair Pro 135cm and wire deescalation was performed to track intra-vessel by using Sion Black.3:  Super selective injection to visualize collateral channel by pure Gd-based contrast with Caravel4:  negotiated apical channel by Sion and successfully navigated into LAD distal true lumen. 5:  Antegrade kissing wire technique by Miracle Neo3 andpassed to distal true lumen.6:  Rewiring for separated D3 branch by using tip detection method with IVUS guidance by Confienza Pro12. 7:  Implanted 2DESs for LAD8:  Inserted C-stopper coils due to tiny apical channel perforation to obtain hemostat.9:  Final Angiography. 
The total Gd-based contrast was used only 15 mmol (15 mL).


Case Summary

We performed successful CTO-PCI in patient with anaphylactic shock for iodinated-based contrast by using gadolinium-based contrast. However, there were no gadorinium-related comorbidity during CTO-PCI. Less visibility in fluoroscopy, limitated amount of contrast use and its cost led difficulty in complex PCI like this case. 

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