E-Abstract

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2024. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-011

Ten-Year Outcomes Post Percutaneous Coronary Intervention in Cardiac Transplant Recipients

By Vinayak Nagaraja, Bradley Lewis, Mandeep Singh

Presenter

Vinayak Nagaraja

Authors

Vinayak Nagaraja1, Bradley Lewis1, Mandeep Singh1

Affiliation

Mayo Clinic, USA1
View Study Report
TCTAP A-011
ACS/AMI

Ten-Year Outcomes Post Percutaneous Coronary Intervention in Cardiac Transplant Recipients

Vinayak Nagaraja1, Bradley Lewis1, Mandeep Singh1

Mayo Clinic, USA1

Background

Cardiac allograft vasculopathy (CAV) is one of themajor late causes of mortality in cardiac transplant recipients beyond thefirst year. Given the lack of longer term data for PCI in cardiac transplantrecipients, we report ten year follow up of such cardiac transplant recipientswho underwent PCI at Mayo Clinic.

Methods

A retrospective observational study was conductedthat included cardiac transplant recipients who underwent PCI at the MayoClinic. Continuous variables were presented as mean (SD) or median (IQR) anddiscrete variables were presented as frequency (percentage). 

Results

Thirty-eight consecutive cardiac transplant recipientsunderwent PCI from January 1, 1995, to June 30, 2023, at the Mayo Clinic. Themedian age of the cohort was 61.00 years (IQR:51.00-70.00) comprised predominantlyof men (65.80%), and 47.40% of the cohort presented with an acute coronarysyndrome. The antirejection therapy prior to the PCI included steroids (47.30%),cyclosporine (26.30%), tacrolimus (15.80%), mycophenolate (42.10%),azathioprine (13.10%), & sirolimus (31.57%).  Intravascular ultrasound during PCI wasutilized in 10.50% of the cases. The median time duration between hearttransplant and PCI was 9.00 years (IQR:6.00-13.00 years). Two individualsneeded repeat heart transplant for severe CAV. In hospital mortality was 5.20%and the long-term median survival was 7.20 years with a 10-year mortality rateof 65.70%.

Conclusion

This is the first publication reporting ten-yearoutcomes for PCI in cardiac transplant patients. The salient features for ourcohort were a 65.70% mortality rate at 10 years and a median survival of 7.20years.