Lots of interesting abstracts and cases were submitted for TCTAP 2024. Below are the accepted ones after a thorough review by our official reviewers. Don’t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!
TCTAP A-022
Risk Factors of Premature Coronary Artery Disease Among Patient Underwent Percutaneous Coronary Intervention in Saiful Anwar General Hospital, East Java Province
By Nikhen Noverike, Muhammad Saifur Rohman
Presenter
Nikhen Noverike
Authors
Nikhen Noverike1, Muhammad Saifur Rohman1
Affiliation
Universitas Brawijaya - Saiful Anwar General Hospital, Indonesia1
View Study Report
TCTAP A-022
Clinical Trials & Science
Risk Factors of Premature Coronary Artery Disease Among Patient Underwent Percutaneous Coronary Intervention in Saiful Anwar General Hospital, East Java Province
Nikhen Noverike1, Muhammad Saifur Rohman1
Universitas Brawijaya - Saiful Anwar General Hospital, Indonesia1
Background
Coronary Artery Disease (CAD) stands as one of the most prevalent heart conditions and remains a leading cause of global mortality. With an estimated annual toll surpassing 350,000 deaths, CAD affects approximately 154 million individuals, representing a significant fraction of the global disease burden. The prevalence of Premature Coronary Artery Disease (PCAD), occurring in individuals under 55 years in male and 60 in female according to Framingham study, poses substantial health challenges. While modifiable factors like smoking, hypertension, and obesity contribute, non-modifiable elements such as age, gender, and family history of heart diseases also play crucial roles. Despite advancements, predictive evaluation of PCAD remains complex due to multifaceted interactions among genetics, lifestyle, and environmental factors. This study aims to analyse the influential factors contributing to Premature Coronary Artery Disease at Dr. Saiful Anwar Regional General Hospital, East Java Province addressing the critical need for targeted risk assessments in younger populations.
Methods
Data collection was carried out by medical record data. We evaluated 2732 consecutive patients who underwent coronary angiography at our hospital from January 2021 until October 2023; 680 patients diagnosed as having premature CAD (male < 55 years and female < 60 years) were included in our analysis. For each patient, the presence of major coronary risk factors such as family history of CAD, dyslipidaemia, diabetes mellitus, hypertension and cigarette smoking were recorded. Besides, angiographic findings were also recorded. Multiple logistic regression analysis was carried out to prove the relationship between variables, while descriptive tests were carried out on characteristics.
Results
The most common risk factor was cigarette smoking in young men (55.4%). However, the major coronary risk factor was overweight in young women (14.6%). When we compared
two groups to major coronary risk factors, we found that the prevalence of diabetes mellitus and cigarette smoking were significantly higher in young men (cigarette smoking: 55.4% vs. 0.9%, respectively, P < 0.001, diabetes mellitus: 19.9% vs. 12.8%, respectively, P < 0.001). Based on angiographic findings showed a significant higher rate of multivessel disease among PCAD.
Conclusion
This study shown the impact of gender on the coronary risk factor profile in patients with premature CAD who undergo Percutaneous Coronary Intervention at Dr Saiful Anwar Hospital Malang are overweight, hypertension and diabetes mellitus. These findings may be useful for management and risk factor modification of young patients with premature CAD.
-Keywords: premature coronary artery disease, coronary angiography lesions, risk factor