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TCTAP C-174

Complex PCI in Chronic Kidney Disease – Made Possible With a Strategy

By Jesslyn Natalie Hariyanto, Sunanto Ng

Presenter

Jesslyn Natalie Hariyanto

Authors

Jesslyn Natalie Hariyanto1, Sunanto Ng1

Affiliation

Universitas Pelita Harapan, Indonesia1,
View Study Report
TCTAP C-174
OTHERS - Renal Insufficiency and Contrast Nephropathy

Complex PCI in Chronic Kidney Disease – Made Possible With a Strategy

Jesslyn Natalie Hariyanto1, Sunanto Ng1

Universitas Pelita Harapan, Indonesia1,

Clinical Information

Patient initials or Identifier Number

SHLV169069

Relevant Clinical History and Physical Exam

A 61 year old diabetic (controlled), hypertensive, female with hyperthyroidism (controlled) and stage IV CKD presented with CCS 3 angina and dyspnea on exertion. Her cardiopulmonary examination was normal. 2 years prior, angiography revealed diffuse three-vessel CAD with mid LAD calcification. She refused CABG and was managed with medical therapy. However, her angina persisted. We elected to proceed with PCI with special considerations for her reduced renal function. 

Relevant Test Results Prior to Catheterization

Her 12-lead ECG showed normal sinus rhythm with no Q waves and no ST segment and T wave changes. Echocardiography showed an LVEF of 62% without regional wall motion abnormalities. 

Relevant Catheterization Findings

Interventional Management

Procedural Step

Intravenous prehydration was administered for 2 days prior to procedure. Baseline renal function was obtained. PCI was planned to the RCA and LAD with an IVUS-guided minimal contrast approach and orbital atherectomy. 
Diffuse lesions throughout the RCA were predilated with Sapphire 2.0/15. IVUS showed diffuse lesion with moderate calcification, MLA of 2.35 mm2. Lesion preparation was done with Wolverine 3.0/15 (Boston Scientific, USA) stented with Orsiro 3.0/40 and Orsiro 3.5/40 (Biotronik, Germany) and postdilated with NC Pantera Leo 3.25/15 (Biotronik, Germany) and NC Sprinter 3.75/21 (OrbusNeich, Hong Kong). IVUS (Boston Scientific, USA) showed good stent expansion and overlap without malapposition, MSA 7.58 mm2. 

IVUS to the LAD revealed extensive calcification with napkin ring at the mid LAD, MLA of 2.16 mm2. 4 low speed runs of the Diamondback¢ç (Cardiovascular Systems Inc, USA) OAS were delivered to the mid LAD, followed by NC Scoreflex 2.75/20 (OrbusNeich, Hong Kong), stented with Orsiro 2.75/40 and postdilated with Pantera Leo 3.25/15. IVUS showed good stent expansion without edge dissection and malapposition, MSA 8.62 mm2.

The procedure was completed without complications. A total of 23 ml of Iomeron contrast (Bracco Imaging, Italy) was used. Ureum and creatinine remained consistent and eGFR was preserved. She was well at discharge without symptoms. 


Case Summary

The two largest predictors of contrast-induced nephropathy are baseline creatinine and volume of contrast used. In the interest of not tipping over her borderline renal function, a revascularization strategy is possible by opting for a minimal contrast approach supported by short injections, intravascular imaging and preparation of adjunctive calcium modification devices where necessary.