E-Case

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2023. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP C-103

A Case of Coronary Artery Dissection and Perforation in a Severe Three Vessel Coronary Artery Disease With Chronic Total Occlusion

By Simeon Villangca, Patrick Nuique Vera Cruz, Myrtle Shekinah Lopez-Cayco, Glein Sayat, Ronald Santos, Alwyn Susanto, Francisco Dalangin

Presenter

Myrtle Shekinah Lopez-Cayco

Authors

Simeon Villangca1, Patrick Nuique Vera Cruz1, Myrtle Shekinah Lopez-Cayco1, Glein Sayat2, Ronald Santos1, Alwyn Susanto3, Francisco Dalangin1

Affiliation

St. Luke's Medical Center, Philippines1, St Luke's Medical Center, Philippines2, St Lukes Medical Center Quezon City, Philippines3,
View Study Report
TCTAP C-103
CORONARY - Complications (Coronary)

A Case of Coronary Artery Dissection and Perforation in a Severe Three Vessel Coronary Artery Disease With Chronic Total Occlusion

Simeon Villangca1, Patrick Nuique Vera Cruz1, Myrtle Shekinah Lopez-Cayco1, Glein Sayat2, Ronald Santos1, Alwyn Susanto3, Francisco Dalangin1

St. Luke's Medical Center, Philippines1, St Luke's Medical Center, Philippines2, St Lukes Medical Center Quezon City, Philippines3,

Clinical Information

Patient initials or Identifier Number

NM

Relevant Clinical History and Physical Exam

A 67-year old male, hypertensive, diabetic, came in for elective coronary angiogram. Patient is asymptomatic with normal resting echocardiogram but with abnormal stress test (>1.0 mm downsloping ST-segment depression in leads II, III, aVF, V3 to V6). He is a non-smoker, non-alcoholic beverage drinker and denies illicit drug use.Patient¡¯s vital signs are within normal limits. He is overweight; body mass index of 27.8 kg/m2. Physical examination is unremarkable.

Relevant Test Results Prior to Catheterization

ECHOCARDIOGRAMNormal left ventricular geometry. Adequate wall motion and contractility. Calculated ejection fraction of 65.2 % by Simpson's method. Grade I diastolic dysfunction. Normal right ventricle. Mild tricuspid regurgitation.TREADMILL STRESS TEST (MODIFIED BRUCE PROTOCOL)Abnormal Stress Test Stage 2; METS 5More than 1.0 mm horizontal to downsloping ST segment depression in leads II, III, aVF, V3 to V6 at stage 2 to recovery 2.

Relevant Catheterization Findings

The left main coronary artery has a non-significant stenosis at the distal segment.The LAD has a moderate stenosis at early proximal and severe stenosis at late proximal segments. The LCx is diffusely diseased with moderate stenosis at late proximal, severe stenosis at mid segments and moderate stenosis at proximal segment of the OM3 branch.The RCA has near total occlusion at proximal and chronic total occlusion at early mid segments. The more distal segments are seen via collateral vessels.


Interventional Management

Procedural Step

PCI OF LADA 7F catheter (Medtronic Launcher EBU 3.5) insertedCoronary wire (Asahi SionBlue) advancedProximal-mid segment pre-dilated with 2.5 x 15 mm balloon (OrbusNeich Sapphire II Pro)A 3.0 x 34 mm DES (Medtronic Onyx) deployed in proximal-mid segment at 14 atm (3.1 mm)Type B dissection seen at distal end of the stentA 2.75 x 12 mm DES (Medtronic Onyx) deployed in mid segment overlapping the edge of previous stent at 13 atm (2.88 mm)PCI OF RCAA 7F catheter (Medtronic Launcher JR4) insertedCoronary wire (Asahi Fielder XT-R) did not cross mid segment after several attempts; successfully crossed with another wire (Asahi Miracle 6)A 6F guide extension (Boston Scientific Guidezilla) was usedType III perforation seen at mid segmentBalloon tamponade using 2.0 x 18 mm balloon (OrbusNeich Sapphire II NC); inflated at 16 atm (2.07 mm) for 7 minutesNo leak seen afterDistal-proximal segments pre-dilated using 2.0 x 18 mm balloon (OrbusNeich Sapphire II NC)A 150 cm microcatheter (Asahi Caravel) used only to change the wire (Asahi Miracle 6) with another wire (Asahi Sion Blue) via balloon trappingFurther pre-dilatation with 2.5 x 15 mm balloon (OrbusNeich Sapphire II Pro) doneA 2.75 x 48 mm DES (Boston Scientific Synergy) deployed in mid-distal segment at 12 atm (3.01 mm)A 3.5 x 48 mm DES (Boston Scientific Synergy) deployed in proximal-mid segment at 16 atm (3.95 mm)No residual perforation or dissection


Case Summary

Coronary artery perforations and dissections are rare but life-threatening complication of percutaneous coronary intervention. Several risk factors increase the risk of these complications such as chronic total occlusion, old age, diabetes and long lesions. All of these are present in our patient. Immediate recognition is key to effective early management of these problems encountered during the procedure. For this case, overlapping stent in the coronary artery dissection and prolonged balloon inflation in coronary artery perforation controlled further progression. Appropriate management is life-saving.