E-Abstract

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2023. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-045

Outcomes of Acute Kidney Injury on Cardiogenic Shock Requiring Intra-Aortic Balloon Pump: A 10-Year Retrospective Data Review

By Khaled Al Khodari, Alaa Rahhal, Raad Tahtouh, Mohammed Awad Ashour, Eman Shehada, Wael Kanjo, Mohamad Safwan Aljafar, Mona Sofi, Abdelaziz M Tawengi, Mohamed Mahmoud Tawengi, Abdul Rahman Arabi

Presenter

Khaled Al Khodari

Authors

Khaled Al Khodari1, Alaa Rahhal1, Raad Tahtouh1, Mohammed Awad Ashour1, Eman Shehada1, Wael Kanjo1, Mohamad Safwan Aljafar2, Mona Sofi2, Abdelaziz M Tawengi3, Mohamed Mahmoud Tawengi3, Abdul Rahman Arabi1

Affiliation

Hamad Medical Corporation, Qatar1, Hamad Medical Corporation (HMC), Doha, Qatar2, Qatar University, Qatar3
View Study Report
TCTAP A-045
Hemodynamic Support and Cardiogenic Shock

Outcomes of Acute Kidney Injury on Cardiogenic Shock Requiring Intra-Aortic Balloon Pump: A 10-Year Retrospective Data Review

Khaled Al Khodari1, Alaa Rahhal1, Raad Tahtouh1, Mohammed Awad Ashour1, Eman Shehada1, Wael Kanjo1, Mohamad Safwan Aljafar2, Mona Sofi2, Abdelaziz M Tawengi3, Mohamed Mahmoud Tawengi3, Abdul Rahman Arabi1

Hamad Medical Corporation, Qatar1, Hamad Medical Corporation (HMC), Doha, Qatar2, Qatar University, Qatar3

Background

Acute kidney injury (AKI) is a momentous complication in patients with acute myocardial infarction (AMI). It is associated with significant morbidity and mortality, especially in patients with hemodynamic instability. Our aim is to review the effect of AKI on the outcomes in patients with AMI complicated by cardiogenic shock (AMI-CS) who required intra-aortic balloon pump (IABP) insertion.

Methods

This retrospective observational cohort study was conducted at the main tertiary cardiology center in Qatar. We included patients admitted with AMI-CS requiring IABP between January 2012 and December 2021. We divided them into two groups: group I indicates the patients who developed AKI, and group II refers to those without AKI. AKI was defined as an increase in serum creatinine by at least 25% from baseline within 72 hours of hospital admission. Mortality at 30 and 360 days was assessed as well as total and intensive care unit (ICU) length of stay and the incidence of complications, like sepsis, ischemic stroke, and major bleeding. Logistic regression was used to determine the significance of the results with p-value < 0.05 indicating statistical significance.

Results

We included 237 patients admitted with AMI-CS and required IABP insertion during the study period. Renal function test was available for 232 patients. Most of them were male (93%) and Asian (75%). The mean age was 54 +/- 11 years. Chronic Kidney disease (CKD), which is defined as calculated glomerular filtration rate (GFR) of less than 60 ml/min, was present at baseline in 65 patients (27.5%). Overall, AKI occurred in 108 (46.5%) patients. Mortality at 30 and 360 days was significantly higher in group I than group II patients (p-value = 0.002 and less than 0.001, respectively). Patients with AKI had longer total and ICU hospital stay as compared with those without AKI (p-value= 0.009 and less than 0.001, respectively). Sepsis, ischemic stroke, and major bleeding were significantly higher in patients with AKI as summarized in Table 1.

Conclusion

Almost half of AMI-CS patients developed AKI during hospital stay. It is approximately associated with doubled mortality at 30 and 360 days, and it is linked to prolonged hospital stay which adds extra burden to patients and health care facilities. Preventive measures should be intensified in AMI-CS cases.