Clinical and Angiographic Outcomes after Single Drug-Eluting Stent Implantation for Bifurcation Lesions in Diabetic Patients: Sub-Analysis from SINGLE KISS Trial
1The Cardiovascular Institute Hospital, Tokyo, Japan; 2Toyohashi Heart Center, Toyohashi, Japan; 3Sanda City Hospital, Sanda, Japan; 4Shinko Kakogawa Hospital , Kakogawa, Japan; 5Itabashi Chuo Medical Center , Tokyo, Japan; 6Rinku General Medical Center , Izumi Otsu, Japan; 7Southern Tohoku Research Institute for Neuroscience , Koriyama, Japan
Y. Oikawa1, K. Nasu2, R. Yoshikawa3, M. Kadotani4, H. Ohta5, Y. Takeda6, M. Mutoh7, T. Suzuki2, T. Aizawa1
Background: There are limited angiographic and clinical follow-up data after single drug-eluting stent implantation with final kissing inflation (FKI) for bifurcation lesions in diabetic patients.
Methods: From the prospective randomized study of SINGLE KISS trial to assess the efficacy of single stent strategy with FKI using by sirolimus- (SES) and paclitaxel-eluting stents (PES) for 824 bifurcation lesions, 341 lesions in 341 diabetic patients were selected to evaluate one year clinical results and 9 month quantitative angiographic analysis.
Results: The Major Adverse Cardiac Events (MACE) rates between two groups were similar (Table). However, in SES group, MACE rates of diabetic group were significantly higher than non diabetic group.
Conclusion: Single stent strategy with FKI using by SES and PES were similar and effective for bifurcation lesions in diabetic patients.