Background: We recently reported that the Doppler guidewire (DGW) can detect emboli as high-intensity transient signals (HITS) and the number of HITS during PCI was associated with poor recovery of left ventricular function in AMI. In the present study, we cleared the efficacy of FILTRAP¢â during PCI by using DGW in AMI.
Methods: We studied 45 patients with first AMI who underwent PCI within 6 hours after the symptom onset. After coronary thrombectomy, FILTRAP¢â was used in 20 patients and was not used in 25 patients who were monitored by DGW to detect HITS. Peak CPK was measured.
Results: The average number of HITS was 21¡¾23 counts ranging from 0 to 83 counts in the 25 patients without FILTRAP¢â. They were divided into 2 groups according to the number of HITS: HITS < 15 (n=13) and ¡Ã 15 (n=12). There was no significant difference in peak CPK between the 3 groups. In patients with RCA culprit lesions, peak CPK was significantly lower in FILTRAP group (n=11) and HITS < 15 group (n=6) compared to HITS ¡Ã 15 group (n=8) (1811¡¾1403, 1474¡¾782, 3782¡¾3174 IU/L, P<0.05, respectively).
Conclusion: The wide range of the number of emboli during PCI concealed the efficacy of FILTRAP¢â. The classification according to the number of distal emboli in the control group can clear the efficacy of it.
